Endocrine Abstracts

Background: Recent studies have shown that adult human possess active brown adipose tissue (BAT), which might be important in affecting obesity and related metabolic risk. However, the supporting evidence in large population based studies is sparse.Methods: We studied 4011 (2688 males and 1323 females) tumor-free Chinese adults aged 18–89 for BAT activities, visceral/subcutaneous fat areas and metabolic parameters. In vivo 18F-fluorodeoxygluc...

Clear evidence on the specific impact of fatty acid binding proteins (FABPs) on cell biology and lipid metabolism in complex systems had been lacking until FABP-deficient mice models were created. Surprisingly, no change in appearance, gross morphology or viability was observed in FABP1-deficient mice. However, metabolic parameters in mice upon exposure to high-fat/cholesterol diet differed between studies. Therefore, liver fatty acid-binding protein (also called FABP1) plays ...